The Proof Is In The Ingredients:
The use of polysaccharides from botanicals as therapeutic agents has aroused great interest in recent years for their health promoting properties. The concentrated herbal extracts in BloX contain a variety of polysaccharides which work synergistically to strengthen and stimulate the immune system. In addition to the immunomodulatory action of the polysaccharides, this herbal formula also provides a potent blend of lignans and flavonoids, which, along with the polysaccharides, offer anti-inflammatory, antioxidant, cancer protective, and hepatoprotective properties. The ingredients and health benefits of BloX are as follows:
Tiaga (Fomitopsis pinicola): Tiaga is a word derived from the Native Americans, which means, “To give life,” or “Healing” Tiaga is a woody mushroom that grows on certain cone-bearing trees, most commonly in the pacific northwest of the United States. It contains 3-beta-D-glucans which make up part of the cellular structure of this mushroom. These beta-glucans can cause a systemic modulation of T-Cells, Macrophages and Neutrophils (White Blood Cells), when ingested. In fact, it has been established that the number and viability of these particular cells is increased by as much as 4000% within 20 hours after taking Tiaga. Tiaga also contains bitter triterpene compounds that support the thymus and spleen (essential to insuring that immune cells are properly programmed), anti-tumor polysaccharides, blood pressure-reducing angiotensin re-uptake inhibitors, and perhaps the highest source of germanium in nature, an oxygen catalyst and one of the most powerful free-radical scavengers found in nature. Dr. Phillip (Cloudpiler) Landis, National Board Certified Naturopath, President of the Utah Naturopathic Medical Association, has said after extensive review and studies, personal and student use, “In a way only surpassed perhaps by Vitamin C research, the phytoceuticals of Tiaga have been widely studied by medical and pharmacological researchers in leading American research colleges and hospitals. The biologically active components have been so rigorously examined in the laboratory…it is evident that the multiple health benefits of Tiaga are supported by scientific investigation… I am convinced that Tiaga will, without a doubt, entirely eclipse every other natural health supplement ever produced.” (Landis, 2007 http://www.furrykids.net/tsiagha.php).
Agaricus blazei Murrill ( Agaricus Brasiliensis): Researchers in the late sixties discovered a very low incidence of chronic illness, among the local people, such as cancer, diabetes, cardiovascular and heart disease. This discovery led them to believe the AbM mushroom was a contributing factor. AbM mushroom samples were sent to the Pharmacological Department at Tokyo University and the National Cancer Center in Japan , for further evaluation and to establish its effect on cancer. The research primarily focused on the anti-tumor properties of the beta-glucans found in the AbM mushroom and its pharmacological effects. The positive results of the research were presented at the Japan Pharmacological Association and the Japan Cancer Association in 1970 .
The mushroom contains valuable ingredients, such as essential amino acids, vitamins, minerals, vegetable proteins, anti-oxidants, enzymes, dietary crude fibers, natural sterols, Triterpenes, Saponins and polysaccharides which stimulate the immune system. The AbM mushroom consists of a total of 192 nutrients. AbM mushroom have no known side effects and toxicity studies have confirmed its safety. For many years, AbM has been used in hospitals as adjunct nutritional therapy for cancer patients in Brazil, Europe, Japan and other Asian countries. It is the most widely used medicinal mushroom for health maintenance, prevention and for adjunct treatments for a wide range of health concerns.
Coriolus versicolor (Turkey Tail): There has been a growing body of research on Coriolus versicolor—especially in the field of cancer. In fact, Coriolus versicolor is the most researched natural compound with regards to its cancer protective properties. Coriolus versicolor improved blood leukocyte and neutrophil counts, as well as improving serum IgG and IgM levels. (Tsang, et al., 2003). In another study, Coriolus versicolor doubled the number of natural killer cells in eight weeks. (Monro, 2003) Coriolus versicolor also works synergistically with salvia to increase immune function. In one study, the combination of Coriolus versicolor and salvia helped to increase gene expression of interleukin-2 receptor, increase absolute counts of T helper cell and ratio of T suppressor and cytotoxic T cell. (Wong, et al., 2004). Note: Coriolus versicolor is also known as Trametes versicolor and Polyporus versicolor.
Salvia miltiorrhiza (Dan Shen): In addition to its immunopotentiating effects, salvia also contains phenolic compounds which possess a variety of biological activities, including antioxidant, anti-hypertension, antiviral, and anti-tumor properties. (Jiang, 2005). Salvia has been shown to exhibit anti-inflammatory properties in vitro. In one recent study, the water extract of salvia blocked lipopolysaccharide-induced NF-kappa B signaling pathway by targeting the I kappa B kinase complex in intestinal epithelial cells. The I kappa B kinase (IKK) and NF-kappa B are key elements of proinflammatory signaling. Furthermore, the nuclear transcription factor NF-kappa B controls the expression of many genes linked to atherogenesis including those involved with inflammation. The authors of the study concluded that the modulation of bacterial product mediated NF-kappa B signaling by natural plant extracts may represent an attractive strategy towards the prevention and treatment of intestinal inflammation. (Kim et al, 2005)
Grifola frondosa (Maitake mushroom): Maitake has been studied for its immunomodulating activities as well as its anti-cancer properties. Administration of a polysaccharide from maitake was shown to stimulate the immune system in mice (Kodama, et al, 2004). Maitake also activates macrophages, dendritic cells, T cells, and inhibits the growth of tumor cells. (Kodama et al., 2005).
Lentinus edodes (Shiitake mushroom): Shiitake acts as an immune stimulant and immunomodulator. It increases T cells, natural killer cells, macrophages, and has antitumor activity. The polysaccharide component of shiitake, lentinan, also stimulates production of antiviral immunoglobulins, enhances production of antibodies, increases interferon levels and interleukin 1 (Hobbs, 1986). Shiitake works on both cellular mediated and humoral branches of the immune system.
Astragalus membranaceus: Astragalus has been used for thousands of years in Traditional Chinese Medicine (TCM) for its ability to reverse fatigue and to help with recovery from a variety of chronic illnesses. Recent research has substantiated the immunopotentiating effects of astragalus. Astragalus has been shown to stimulate macrophage to produce interleukin-6 and tumor necrosis factor. It inhibits viral replication, and it has in vitro antibacterial properties. (Alt Med Rev, 2003) Astragalus also has cardiovascular protective properties—it increases contraction of normal hearts and in animal studies it has been shown to lower blood pressure. (Hsu, 1988).
Lycium barbarum: Much of the research on lycii berries has been done on its immunomodulatory properties. In addition, lycii berry produced a significant immunomodulatory effect by increasing natural killer and lymphokine activated killer cell activity. (Cao et al., 1994). In addition, lycii berry was also shown to increase macrophage phagocytosis, spleen lymphocyte proliferation, cytotoxic T lymphocyte activity, and interleukin 2 mRNA expression in mice. (Gan et al., 2004). Also, in an in vitro study, a polysaccharide-protein complex from lycium fruit upregulated cytokine expression in human peripheral blood mononuclear cells (Gan et al., 2003).
Thus, the herbal extracts in this product were formulated and blended according to the principles of Traditional Chinese Medicine that seek to restore balance and harmony of the bodies organ systems, metabolic functions (Yin and Yang), and energetic properties (Chi). When the whole body is brought into balance the immune system will be strengthened and better able to keep pathogens from having a chance to invade, multiply and develop into chronic degenerative conditions. Increased resistance to colds and flu and better overall energy and well-being will result from having a healthier immune system supported by this proprietary Chinese tonic herbal formula.
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539 Parrott St., San Jose, CA 95112 408-287-7871 408-287-8838 fax Confidential 3 for internal review only NuWorld Immune Formula
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